Did you know in 1996 Seth Macfarlane made a pilot for Cartoon Network called Larry and Steve? It happened. Peter, Brian, and Quagmire were all a part of the show as slightly askew versions of their present selves.
Check it out, it's a Family Guy made just for twelve year olds and people that like animated pratfalls more than bizarre sexual innuendo based on eighties primetime.
UPDATE: It seems Larry and Steve go back even farther, check out this short from Macfarlane's days at RISD.