@Henry Baker: Definitely - the Up sequence is gut-wrenching and achingly beautiful, but That Episode (seriously, I will not speak its name) just makes me want to vomit out of sorrow and despair. I think it's because Up turns out to be, well, uplifting, while That Episode just ends with ... that scene. Gah.
And as nice as it was of the writers to add that silver lining to the Seymour storyline in the first Futurama movie, I still can't watch That Episode. It's dogs, man. Dogs. Hollywood can kill a million babies on screen and I can handle it, but don't ever make me watch the end of Marley & Me. That book shattered me. SHATTERED.
I really need to hug my dogs now. They're such good babies, and THEY WILL LIVE FOREVER. Don't tell me differently. FOREVER.