The premiere Family Guy was an hour-long mystery done in the classic style of "whodunnit" movies. Admittedly sick of Family Guy's same-old-shtick, it was surprisingly plot-driven and delightful to watch. Because it's easily watched online, this post is spoiler-free!
The Set-up: Almost the entirety of Quahog received letters in the mail stating they were invited to a dinner hosted in their honor. Peter and his family hop in the car and realize as soon as they arrive at the mansion of James Woods that something fishy is going on.
Here's the show's introduction, which can give you an idea of what the episode was like:
[There was a video here]