According to TMZ, Perlman and DeVito met in 1970 at an off-Broadway play called The Shrinking Bride, which starred a friend of Perlman's. DeVito's performance so captivated her that she was instantly smitten.
Though their impending divorce was officially confirmed by a rep, no word has been released so far on why the the Matilda co-stars have decided to split after such a long time together.
The now-former lovers share three children: Lucy Chet, Grace Fan, and Jacob Daniel.
[photo via AP]